Please use this identifier to cite or link to this item: http://ds.saudeindigena.icict.fiocruz.br/handle/bvs/1039
Title: Prevalence and factors associated with latent tuberculosis infection in an indigenous population in the Brazilian Amazon
Authors: Malacarne, Jocieli
Rios, Diana Patrícia Giraldo
Silva, Cosme Marcelo Furtado Passos da
Braga, José Ueleres
Camacho, Luiz Antonio Bastos
Basta, Paulo Cesar
Affilliation: Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Epidemiologia e Métodos Quantitativos em Saúde. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Epidemiologia e Métodos Quantitativos em Saúde. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Epidemiologia e Métodos Quantitativos em Saúde. Rio de Janeiro, RJ, Brasil.
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil.
Abstract: INTRODUCTION Recent studies have shown a high incidence and prevalence of latent tuberculosis infection (LTBI) in indigenous populations around the World. We aimed to estimate the prevalence and annual risk of infection (ARI) as well as to identify factors associated with LTBI in an indigenous population from the Brazilian Amazon. METHODS We conducted a cross-sectional study in 2011. We performed tuberculin skin tests (TSTs), smears and cultures of sputum samples, and chest radiographs for individuals who reported cough for two or more weeks. Associations between LTBI (TST ≥5mm) and socio-demographic, clinical, and epidemiological characteristics were investigated using Poisson regression with robust variance. Prevalence ratio (PR) was used as the measure of association. RESULTS We examined 263 individuals. The prevalence of LTBI was 40.3%, and the ARI was 2.4%. Age ≥15 years [PR=5.5; 95% confidence interval (CI): 3.5-8.6], contact with tuberculosis (TB) patients (PR=3.8; 95% CI: 1.2-11.9), previous TB history (PR=1.4; 95% CI: 1.2-1.7), and presence of Bacillus Calmette-Guérin (BCG) scar (PR=1.9, 95% CI: 1.2-2.9) were associated with LTBI. CONCLUSIONS Although some adults may have been infected years prior, the high prevalence of infection and its strong association with age ≥15 years, history of TB, and recent contact with TB patients suggest that the TB transmission risk is high in the study area.
Keywords: Brasil
Índios Sul-Americanos
Região Norte
Região Amazônica
Epidemiologia
Rondônia
Tuberculose
Pakaanova
Serviços de Saúde
Estudos Epidemiológicos
Wari´
Radiografia
Desigualdades em Saúde
Doenças Infecciosas e Parasitárias
Saúde de Populações Indígenas
Condições Socioeconômicas
Teste Tuberculínico
Exame Radiológico
Issue Date: 2016
Publisher: Sociedade Brasileira de Medicina Tropical - SBMT
Citation: MALACARNE, Jocieli; RIOS, Diana Patricia Giraldo; SILVA, Cosme Marcelo Furtado Passos da; BRAGA, José Ueleres; CAMACHO, Luiz Antonio Bastos; BASTA, Paulo Cesar. Prevalence and factors associated with latent tuberculosis infection in an indigenous population in the Brazilian Amazon. Revista da Sociedade Brasileira de Medicina Tropical, v. 49, n. 4, p. 456-464, 2016.
metadata.dc.identifier.doi: 10.1590/0037-8682-0220-2016
ISSN: 0037-8682
Copyright: open access
Appears in Collections:DIP - Artigos de Periódicos
EPI - Artigos de Periódicos

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