Please use this identifier to cite or link to this item: http://ds.saudeindigena.icict.fiocruz.br/handle/bvs/1319
Title: Endemic pemphigus foliaceus (fogo selvagem) in Native Americans from Brazil
Authors: Friedman, Horacio
Campbell, Iphis
Rocha-Alvarez, Rosicler
Ferrari, Iris
Coimbra Junior, Carlos E. A.
Moraes, Jose R.
Flowers, Nancy M.
Stastny, Peter
Fernanez-Vinã, Marcelo
Olague-Alcala, Monica
Diaz, Luis A.
Affilliation: Universidade de Brasília. Brasilia, DF, Brasil
Universidade de Brasília. Brasilia, DF, Brasil
Universidade de Brasília. Brasilia, DF, Brasil
Universidade de Brasília. Brasilia, DF, Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil
Universidade de São Paulo. Escola Paulista de Medicina. São Paulo, SP, Brasil
Universidade da cidade de Nova York. Nova York, EUA
Universidade do Texas. EUA
Universidade do Texas. EUA
Medical College of Wisconsin. Milwaukee, EUA
Medical College of Wisconsin. Milwaukee, EUA
Abstract: Fogo selvagem (FS) is an autoimmune disease that is endemic in certain regions of Brazil and appears to be precipitated by an environmental factor. Objective: Our purpose was to confirm the occurrence and prevalence of FS in a population of Xavante Indians living in an endemic region of central Brazil. Methods: Clinical, anthropologic, and immunologic studies were carried out in patients and in normal inhabitants of the Pimentel Barbosa Indian Reservation, Mato Grosso, Brazil. Results: FS was identified and confirmed in 10 patients from a patient pool of 295 with various skin diseases. The Xavante settlement has a total population of 746. Anti-desmoglein 1 autoantibodies were detected in all patients with FS and were absent from more than 300 serum samples collected from randomly selected unaffected persons. Conclusion: FS is strongly linked to outdoor activities and is largely restricted to immunogenetically predisposed persons. FS appears to have been endemic in certain regions of South America for several centuries.
Keywords: Brasil
Índios Sul-Americanos
Saúde de Populações Indígenas
Mato Grosso
Região Amazônica
Região Centro-Oeste
Xavante
Antropologia Cultural
Fogo Selvagem
Dermatopatias
Endemias
Pênfigo Brasileiro
Doenças de Pele e do Tecido Subcutâneo
Procedimentos Clínicos
DeCS: Brasil
Saúde de Populações Indígenas
Índios Sul-Americanos
Ecossistema Amazônico
Antropologia Cultural
Pênfigo
Dermatopatias
Issue Date: 1995
Publisher: American Academy of Dermatology
Citation: FRIEDMAN, Horacio; et al. Endemic pemphigus foliaceus (fogo selvagem) in Native Americans from Brazil. Journal of the American Academy of Dermatology, v. 32, n. 6, p. 949-956, 1995.
metadata.dc.identifier.doi: 0190-9622/95 $3.00+0 16
Other Identifiers: 0190-9622/95 $3.00 + 0 16
Copyright: open access
Appears in Collections:TR - Artigos de Periódicos

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