Please use this identifier to cite or link to this item: http://ds.saudeindigena.icict.fiocruz.br/handle/bvs/1467
Title: High heterogeneity of apolipoprotein E gene frequencies in South American Indians
Authors: Andrade, F. M. de
Coimbra Junior, Carlos E. A.
Santos, Ricardo Ventura
Goicoechea, A.
Carnese, F. R.
Salzano, Francisco M.
Hutz, Mara H.
Affilliation: Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Porto Alegre, RS Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Museu Nacional. Departamento de Antropologia. Rio de Janeiro, RJ, Brasil
Universidade de Buenos Aires. Escola de Filosofia e Letras. Buenos Aires, Argentina
Universidade de Buenos Aires. Escola de Filosofia e Letras. Buenos Aires, Argentina
Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Porto Alegre, RS Brasil
Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Porto Alegre, RS Brasil
Abstract: The apolipoprotein E (APOE) polymorphism was investigated in 186 individuals from six South American Indian tribes, and the results integrated with those previously presented for this ethnic group. The three APOE alleles commonly reported in other populations were also observed in South Amerindians with a highly heterogeneous distribution. As in other populations, APOE*3 was the most common allele (51-98%) followed by APOE*4 (2-47%). These two isoforms were identified in all tribes, but APOE*2 was observed among the Wai Wai (2%) and Mataco (4%) only. No previous indications of inter-ethnic admixture were observed among the Wai Wai, but the introduction of this allele among the Mataco through non-Indian sources cannot be excluded.
Keywords: Brasil
Índios Sul-Americanos
Região Norte
Saúde de Populações Indígenas
Mato Grosso
Região Amazônica
Epidemiologia
Pará
Região Centro-Oeste
Gavião
Suruí
Rondônia
Xavante
Zoró
Argentina
Wai Wai
Estudos Epidemiológicos
Genética Humana
Mataco
DeCS: Brasil
Saúde de Populações Indígenas
Índios Sul-Americanos
Ecossistema Amazônico
Epidemiologia
Genética Humana
Estudos Epidemiológicos
Issue Date: 2000
Publisher: Taylor & Francis
Citation: ANDRADE, F. M. de; et al. High heterogeneity of apolipoprotein E gene frequencies in South American Indians. Annals of Human Biology, v. 27, n.1, p. 29-34, 2000.
metadata.dc.identifier.doi: 10.1080/030144600282352
ISSN: 0301-4460
1464-5033
Copyright: open access
Appears in Collections:GH - Artigos de Periódicos

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