Please use this identifier to cite or link to this item: http://ds.saudeindigena.icict.fiocruz.br/handle/bvs/1487
Title: Tuberculosis control in a highly endemic indigenous community in Brazil
Authors: Croda, Mariana Garcia
Trajber, Zelik
Lima, Rosangela da Costa
Croda, Julio Henrique Rosa
Affilliation: Universidade Federal de Grande Dourados. Hospital Universitário. Dourados, MS, Brasil.
Ministério da Saúde. Fundação Nacional de Saúde. Dourados, MS, Brasil
Universidade Federal de Grande Dourados. Dourados, MS, Brasil
Universidade Federal de Grande Dourados. Dourados, MS, Brasil
Abstract: In Latin America, indigenous populations have high rates of non-completion of TB treatment and case fatality and have been defined as a priority group for investments. To evaluate TB control, a retrospective cohort study was performed to identify factors predictive of non-completion of treatment and mortality in an indigenous and non-indigenous population between 2002 and 2008 in Dourados, Brazil. A 90% reduction in non-completion of TB treatment was observed in the indigenous population after DOTS (directly observed treatment, short course) implementation (20% vs 2%). In the non-indigenous population, the number of patients not completing TB treatment continued to increase. Non-indigenous TB patients had 4.5 times higher mortality than indigenous TB patients (9% vs 2%). In multivariate analysis, non-indigenous race [odds ratio (OR) 2.33, 95% CI 1.32-4.10] was associated with non-completion of TB treatment, and HIV-positive status (OR 5.58, 95% CI 2.38-13.07) was associated with mortality. Implementation of DOTS in the indigenous populations in Dourados showed a significant reduction in non-completion of TB treatment. Nevertheless, a high rate of TB in children and young adults indicates the continuous transmission and maintenance of the epidemic in this community. Among the non-indigenous population, the TB case fatality rate is closely linked to the HIV prevalence.
Keywords: Brasil
Índios Sul-Americanos
Saúde de Populações Indígenas
Epidemiologia
Região Centro-Oeste
Mato Grosso do Sul
Tuberculose
Fatores de Risco
Estudos Epidemiológicos
Doenças Infecciosas
DeCS: Brasil
Saúde de Populações Indígenas
Índios Sul-Americanos
Epidemiologia
Tuberculose
Fatores de Risco
Doenças Infecciosas
HIV
Issue Date: 2012
Publisher: Oxford University Press
Citation: CRODA, Mariana Garcia; et al. Tuberculosis control in a highly endemic indigenous community in Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 106, p. 223-229, 2012.
metadata.dc.identifier.doi: 10.1016/j.trstmh.2012.01.005
ISSN: 1878-3503
Copyright: open access
Appears in Collections:EPI - Artigos de Periódicos

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