Please use this identifier to cite or link to this item: http://ds.saudeindigena.icict.fiocruz.br/handle/bvs/6939
Title: Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil
Authors: Black, Francis L.
Salzano, Francisco M.
Layrisse, Zulay
Franco, M. Helena L. P.
Harris, Nancy S.
Weimer, Tania A.
Affilliation: Yale University School of Medicine. Department of Epidemiology and Public Health. New Haven, CT, USA.
Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.
Instituto Venezolano de Investigaciones Científicas. Caracas, Venezuela.
Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.
Yale University School of Medicine. Department of Epidemiology and Public Health. New Haven, CT, USA.
Universidade Federal do Rio Grande do Sul. Instituto de Biociências. Departamento de Genética. Porto Alegre, RS, Brasil.
Abstract: Results concerning HLA types and 22 other blood genetic systems are reported for the Parakanã Indians of northern Brazil, a tribe that is notable for the light color and pilosity of some of its members. No clear evidence of Caucasoid admixture was found, but the Parkanã show unusual frequencies in the EsD¹, PGM¹₁, Gc², Cpᴮ, Fyᵃ, Diᵃ, and Lᴹ genetic markers. In addition, the very rare Rh allele rʸ is present, as well as what seems to be a new PGM₂ variant. There is very limited heterogeneity in the HLA system. All these distinctive features may have arisen through a combination of founder effects and genetic drift. However, low Fᵢₛ values, as well as higher mean ages in heterozygous as compared to homozygous persons, suggest that an heterotic effect is counteracting these dispersive forces.
Keywords: Região Norte
Parakanã
Grupo Sanguíneo
DeCS: Brasil
Índios Sul-Americanos
Saúde de Populações Indígenas
Antígenos HLA
Enzimas
Antígenos de Grupos Sanguíneos
Proteínas Sanguíneas
Issue Date: 1980
Publisher: Wiley
Citation: BLACK, Francis L. et al. Restriction and persistence of polymorphisms of HLA and other blood genetic traits in the Parakanã Indians of Brazil. American Journal of Physical Anthropology, v. 52, n. 1, p. 119-132, Jan. 1980.
metadata.dc.identifier.doi: 10.1002/ajpa.1330520115
ISSN: 0002-9483
Copyright: restricted access
Appears in Collections:TR - Artigos de Periódicos

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