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dc.contributor.authorIntersalt Cooperative Research Group-
dc.identifier.citationINTERSALT COOPERATIVE RESEARCH GROUP. Intersalt: An international study of electrolyte excretion and blood pressure: results for 24 hour urinary sodium and potassium excretion. British Medical Journal, v. 297, n. 6644, p. 319-328, July 1988.en_US
dc.publisherBMJ Publishing Groupen_US
dc.rightsopen accessen_US
dc.subject.otherRegião Amazônicaen_US
dc.subject.otherRegião Oesteen_US
dc.subject.otherDoenças e Agravos Não Transmissíveisen_US
dc.titleIntersalt: An international study of electrolyte excretion and blood pressure: results for 24 hour urinary sodium and potassium excretionen_US
dc.description.abstractenThe relations between 24 hour urinary electrolyte excretion and blood pressure were studied in 10,079 men and women aged 20-59 sampled from 52 centres around the world based on a highly standardised protocol with central training of observers, a central laboratory, and extensive quality control. Relations between electrolyte excretion and blood pressure were studied in individual subjects within each centre and the results of these regression analyses pooled for all 52 centres. Relations between population median electrolyte values and population blood pressure values were also analysed across the 52 centres. Sodium excretion ranged from 0.2 mmol/24 h (Yanomamo Indians, Brazil) to 242 mmol/24 h (north China). In individual subjects (within centres) it was significantly related to blood pressure. Four centres found very low sodium excretion, low blood pressure, and little or no upward slope of blood pressure with age. Across the other 48 centres sodium was significantly related to the slope of blood pressure with age but not to median blood pressure or prevalence of high blood pressure. Potassium excretion was negatively correlated with blood pressure in individual subjects after adjustment for confounding variables. Across centres there was no consistent association. The relation of sodium to potassium ratio to blood pressure followed a pattern similar to that of sodium. Body mass index and heavy alcohol intake had strong, significant independent relations with blood pressure in individual subjects.en_US
dc.subject.decsÍndios Sul-Americanosen_US
dc.subject.decsSaúde de Populações Indígenasen_US
dc.subject.decsEcossistema Amazônicoen_US
dc.subject.decsConsumo de Bebidas Alcoólicasen_US
dc.subject.decsAnálise de Regressãoen_US
dc.subject.decsFatores Etáriosen_US
dc.subject.decsFatores Sexuaisen_US
dc.subject.decsPressão sanguíneaen_US
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