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Title: Prevalence of IgC Varicella Zoster virus antibodies communities in Xingu National Park, Brazil, beffore varicella vaccination
Authors: Lafer, Manuel Mindlin
Affilliation: Division of Pediatric Infectious Diseases, Federal University of São Paulo, São Paulo, SP, Brazil
Abstract: The purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples - volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% - 86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.
Keywords: Brasil
Índios Sul-Americanos
Mato Grosso
Parque Indígena do Xingu
Região Amazônica
Região Centro-Oeste
Estudos Epidemiológicos
Pesquisa Qualitativa
Doenças Infecciosas e Parasitárias
Issue Date: 2005
Publisher: Instituto de Medicina Tropical
Citation: LAFER, Manuel Mindlin. Prevalence of IgC Varicella Zoster virus antibodies communities in Xingu National Park, Brazil, beffore varicella vaccination.. Revista do Instituto de Medicina Tropical de São Paulo, v. 47, n. 3, p. 139-142, 2005.
metadata.dc.identifier.doi: 10.1590/S0036-46652005000300004
Copyright: open access
Appears in Collections:DIP - Artigos de Periódicos
EPI - Artigos de Periódicos

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